ACMG/AMP Calculator · Bayesian System
From evidence to classification.
Apply the ACMG/AMP criteria and generate the classification with automatic Bayesian scoring.
Score 0
0 of 26 criteria evaluated
General definitions
Criterion definitions follow the general ACMG/AMP guidelines (Richards et al. 2015). For genes or diseases with their own specification published by a ClinGen VCEP (CSpec), the criteria and thresholds may differ from those described here — consult the gene-specific specification when available.
PVS1
PM4
BP1
BP3